Corticosteroids for diabetic macular edema

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Pharmacology of Corticosteroids for Diabetic Macular Edema.

Purpose Corticosteroids remain the mainstay of treatment for inflammatory diseases almost 80 years after their first clinical use. Topical ophthalmic formulations of corticosteroids have been available to treat disease of the anterior segment of the eye, but the approval of corticosteroids to treat vitreoretinal diseases, including vein occlusion, diabetic macular edema, and uveitis, has occurr...

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Update on corticosteroids for diabetic macular edema

Diabetic macular edema (DME) remains an important cause of visual loss. Although anti-vascular endothelial growth factor (VEGF) agents are generally used as first-line treatments for patients with center-involving DME, there is an important role for corticosteroids as well. Corticosteroids may be especially useful in pseudophakic patients poorly responsive to anti-VEGF therapies, in patients wi...

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Intravitreal Corticosteroids in Diabetic Macular Edema

Purpose: To review the relationship between kinetics, efficacy, and safety of several corticosteroid formulations for the treatment of diabetic macular edema. Methods: Reports of corticosteroid use for the treatment of diabetic macular edema were identified by a literature search, which focused on the pharmacokinetics, efficacy, and safety of these agents in preclinical animal models and clinic...

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Remote Ischemic Preconditioning and Diabetic Macular Edema

Objective: Remote Ischemic Preconditioning (RIPC) as the transient ischemia and reperfusion of the arm is a promising method for protecting different tissue from future ischemia. These effects might be mediated through vascular and endothelial growth factor (VEGF) pathway. We investigated the influence of RIPC on diabetic macular edema (DME) as a chronic ischemic condition in patients who were ...

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Diabetic Macular Edema

Introduction Over the last one decade the management of diabetic macular edema has undergone a paradigm change. This is attributed to the newer diagnostic tests and pharmacological agents. There are enough good randomized controlled trials to prove the efficacy of these drugs. However, in clinical practice, there are many situations where the application of the findings of these clinical trials...

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ژورنال

عنوان ژورنال: Taiwan Journal of Ophthalmology

سال: 2019

ISSN: 2211-5056

DOI: 10.4103/tjo.tjo_68_19